49ers QB Brock Purdy (toe) is questionable to play in Week 10 against the Rams.

07 November 2025

49ers head coach Kyle Shanahan told reporters on Thursday that a decision on whether Purdy will “suit up” would be made this afternoon. Apparently, that decision is a “maybe,” though only as the backup, if active. 49ers QB Mac Jones will once again serve as the team’s starter. He profiles as a high-end QB2 against the Rams’ tough defense.