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Seahawks ruled out Sam Darnold (glute) for Week 2 against the Cardinals.

16 September 2026

The Seahawks will roll with QB Drew Lock as this week’s starter. He is backed up by QB Jalen Milroe. Seahawks coach Mike Macdonald said he does not “anticipate” putting Darnold on injured reserve, so he should be back before Week 6. Lock can be treated as a volatile QB2 against the Cardinals this week.

D.J. Reed (foot) is questionable for Week 2 against the Bills.

16 September 2026

Reed was a mid-week addition to the injury report because of his foot issue. He was limited for the final two practices of the week. Reed is likely on the optimistic side of questionable, but we won’t know for sure until the Lions release their inactives 90 minutes before kickoff.

Ravens placed WR Ja’Kobi Lane on injured reserve with a wrist injury.

16 September 2026

Lane underwent surgery to address a fracture in his wrist and will now miss at least four games on short-term injured reserve. He will be eligible to return in Week 6. Ravens No. 1 WR Zay Flowers (hamstring) is also nursing an injury. Theoretically, fellow rookie WR Elijah Sarratt should be active in Week 2 against the Saints, though it is unclear if he would have a meaningful role if Flowers plays.

Chargers coach Jim Harbaugh said WR Ladd McConkey (rib) will not practice on Wednesday.

16 September 2026

Sitting out on a Wednesday is not the end of the world for established starters. However, this does push McConkey further into the questionable column. The Chargers signed WR Marquez Valdes-Scantling yesterday. Although Valdes-Scantling is unlikely to meaningfully contribute, the fact that the team felt they needed to bring in an extra wide receiver is slightly concerning. McConkey still has two days to get right. If he returns tomorrow, that would be great news.

Vikings placed RB Jordan Mason on injured reserve with a thumb injury.

16 September 2026

That escalated quickly. On Monday, Vikings coach Kevin O’Connell said Mason’s “sore thumb” was being evaluated. Apparently, it had sustained a small fracture, which has now been “fixed,” ostensibly surgically, given O’Connell’s phrasing. Short-term injured reserve placement requires players to miss four games, but the Vikings are on bye in Week 6, so Mason will be eligible to return in Week 7. Mason led the backfield with 15 carries in Week 1, so his absence provides RB Aaron Jo ...

Kyler Murray (concussion) was limited in Wednesday’s practice.

16 September 2026

Murray was knocked out of Week 1 after just a few snaps when he took a late hit directly to his helmet from a Green Bay defender. A limited practice today means he is already making progress through the league’s concussion protocol. He is arguably on the positive side of questionable to start the week. Murray would be a borderline QB1 in versus Chicago’s awful defense if he clears the protocol ahead of Sunday. Carson Wentz will draw the start if Murray isn’t available.

Chiefs placed Cooper McDonald (knee) on injured reserve.

16 September 2026

NFL insider Jordan Schultz reports McDonald is expected to return this season. McDonald was a core special teamer last year. He suffered a knee injury on his second snap of Week 1.

49ers placed TE Jake Tonges on injured reserve with a knee injury.

16 September 2026

Tonges injured his MCL in Week 1. His return timeline has not yet been reported. With Tonges sidelined, TE George Kittle’s ramp-up period could be expedited. Backup TE Luke Farrell should also see more playing time, though he is not fantasy-relevant. The 49ers correspondingly promoted WR KhaDarel Hodge to the active roster and signed TE Jack Stoll.

Tua Tagovailoa (oblique) will not practice on Wednesday.

16 September 2026

This all but rules him out for Week 2. Cooper Rush is getting treatment for the back injury he played through in Week 1 and can also be considered questionable. With Michael Penix not quite ready to return from his 2025 knee injury yet, the Falcons could be down to Jack Strand for their date with the Panthers.

The Cincinnati Enquirer’s Kelsey Conway reports that Bengals QB Joe Burrow skipped team stretches and does not appear to be participating in throwing drills.

16 September 2026

Burrow is seemingly set for a limited session on Wednesday. He is not wearing pads and is reportedly “doing handoffs in a helmet and jersey.” This could simply be a planned load management day. Burrow will speak to the media after practice, so we could get an update later today.

Dolphins placed Kyle Louis (MCL) on injured reserve.

16 September 2026

Louis suffered an MCL sprain in Week 1. He was initially expected to miss a few weeks, and now that number will be at least four while he’s on injured reserve. The team signed cornerback Jaylin Simpson to their active roster in a corresponding move.

Jalen McMillan (knee) is practicing in full on Wednesday.

16 September 2026

McMillan missed Week 1 due to a knee issue, despite getting in three limited practices during the week. He was listed as doubtful and the team ruled him out ahead of kickoff. It seems like the team was taking a cautious approach with his return from the training camp injury, and he should be good for Week 2. McMillan is expected to take rookie Ted Hurst’s spot in the lineup at X. Hurst managed just three catches for 36 yards in the role. In his first game of the season, McMillan will be burie ...

Patriots coach Mike Vrabel said he thinks TreVeyon Henderson (ankle) will “be able to do some more” during Wednesday’s practice.

16 September 2026

Vrabel told reporters Henderson was expected to practice on Monday, so it sounds like the first steps in his return to play are going as planned. He will presumably be limited for today’s session. Rhamondre Stevenson was dreadfully inefficient in Week 1, averaging 2.8 yards per carry on 18 attempts. The Pats desperately need a spark on offense, and Henderson should give that to them once he’s healthy.

ESPN’s Dan Franziano reports Brock Bowers’ knee injury is not “overly serious” and it’s possible he plays in Week 2 against the Chargers.

16 September 2026

Bowers underwent a meniscus trim just before the start of the season and missed Week 1. According to Graziano’s sources, “The team felt he could have played last week if necessary.” That would have been an absurdly quick turnaround for a meniscus trim procedure, though Bowers is already known as a player who tries to push through serious injuries. Graziano added that the latest he thinks Bowers will play is Week 4, which is good news for fantasy managers. Michael Mayer will continue to st ...

Zay Flowers (hamstring) was not seen participating in Wednesday’s practice.

16 September 2026

It’s possible Flowers gets in some light work after the media portion of the practice, but this should go down as a DNP. Flowers left the Ravens’ Week 1 win over the Colts in the first half. He already had 150 yards and a touchdown to his name. The hamstring issue isn’t believed to be serious, but the team may want to take a cautious approach and hold him out for a week. With Ja’Kobi Lane out because of a broken wrist, Rashod Bateman and Mark Andrews would be the top targets for Lamar J ...

Tyrone Tracy (illness) did not practice Wednesday.

16 September 2026

Tracy has the flu, according to head coach John Harbaugh. He said the hope is that Tracy is back for tomorrow’s practice. Tracy was demoted from the RB2 role in Week 1 after losing a fumble on his second carry of the night. He did not play a snap on offense after the turnover. The missed practice time this week could be reason enough for the Giants to make him inactive in favor of Najee Harris on Sunday. Either way, Tracy is not worth stashing even in deep fantasy leagues.

Chig Okonwko (hamstring) did not practice Wednesday.

16 September 2026

Okonkwo left Week 1 in the third quarter with the hamstring issue and did not return. A DNP today puts him on the wrong side of questionable for Week 2. John Bates and Ben Sinnott each ran 10 routes on Sunday. They would likely split Okonkwo’s role if he can’t suit up, meaning their isn’t much fantasy value to be had here.

Chiefs coach Andy Reid said “there’s a pretty good chance” Mansoor Delane (shoulder) is in uniform and available for Week 2 against the Colts.

16 September 2026

Delane left Week 1 with a right shoulder injury and did not return. He underwent X-rays after exiting the game and the results were negative. Reid specifically said he expects Delane to be available, but that doesn’t rule out a reserve role if the team wants to play it safe with the rookie. He is expected to practice today, presumably in a limited capacity.

49ers promoted KhaDarel Hodge to the team’s active roster.

16 September 2026

This comes as the Niners placed rookie WR De’Zaun Stribling (ankle) on injured reserve, meaning he’ll be sidelined for at least four weeks. Hodge isn’t likely to see many snaps or routes this week against the Dolphins and should remain on waiver wires.

Falcons head coach Kevin Stefanski said QB Cooper Rush is getting treatment for a back injury.

16 September 2026

Stefanski on Wednesday wouldn’t rule out any of his four quarterbacks of the apocalypse, including rookie QB Jack Strand, who flashed in preseason action against second and third-team defenses. Rush as abysmal in the Falcons’ Week 1 loss to the Steelers. He was 10.5 percent below his expected pass rate, throwing for 143 yards, one touchdown, and two picks. There’s almost no way Strand would be a downgrade for Week 2 if he gets the nod. Michael Penix (knee) will continued to be sidelined a ...

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