49ers WR Ricky Pearsall (knee) did not practice on Wednesday.

05 November 2025

Pearsall’s PCL sprain continues to be a problem. The 49ers’ early-season star has not practiced since suffering the injury in Week 4, and yet, the team has chosen not to place him on injured reserve. Pearsall technically has a chance to play if he can practice later this week, but it seems likely we will revisit his availability on Wednesday, next week.