49ers HC Kyle Shanahan said the team will not open Brandon Aiyuk’s (knee) return window this week.

17 November 2025

The Niners continue to push back the return for Aiyuk, who is still working his way back from the season-ending knee injury he suffered in 2024. 49ers general manager John Lynch said last week that the team still plans to get Aiyuk on the field at some point this season, but the timeline for his return remains a mystery. In addition to Aiyuk, the Niners also said they won’t be opening Jacob Cowing’s return window until after their Week 14 bye. Cowing has been sidelined with a hamstring injury.