Colts RB Ameer Abdullah (knee) is practicing fully for Week 16 against the 49ers.

18 December 2025

The 32-year-old is coming off a season-high nine touches, so a sore knee makes sense. He is difficult to trust, even in PPR formats, given the one-game blip, but he appears to be a QB Philip Rivers’ preferred checkdown option. Expect him to handle passing down duties against the 49ers.