49ers coach Kyle Shanahan said DL Mykel Williams (knee) will likely sit out in Week 1 against the Rams.

19 August 2026

This is unfortunate. The second-year pass rusher seemingly had a chance to play right away, but the team is apparently adjusting its expectations. Williams, 22, suffered a season-ending ACL tear in November. Whenever he makes it back, he will provide a decent boost to the 49ers’ defensive line.