49ers placed Isaac Guerendo to the reserve/PUP list.

30 August 2026

Guerendo, still recovering from a pec injury, will miss at least the first four weeks of the regular season. This helps to clarify the Niners backfield situation headed into the season. Behind Christian McCaffrey will be some combination of Kaelon Black — who has drawn praise from coaches and QB Brock Purdy — and Jordan James, who missed most of training camp with a rib injury. Guerendo is a long way from playing time in the Niners offense.