Patrick Mahomes completed 32-of-47 passes for 382 yards and three touchdowns in the Chiefs’ 33-30, Week 2 win over the Colts, adding 17 yards on two carries.

21 September 2026

Mahomes looked much more like himself against the Colts than he did against the Broncos in Week 1, with his typical mobility in the pocket on full display as he extended plays. He even escaped the pocket twice to pick up crucial first downs with his legs in key situations, looking closer to how he did before tearing his ACL in 2025. Mahomes also managed to complete two passes greater than 30 yards, one to Tyquan Thornton and one to Rashee Rice, an area of his game that has not been great the previous two seasons. Even so, it took the Chiefs two possessions in overtime to finally sneak by the tenacious Colts, moving to a 2-0 record ahead of a road date with the Dolphins in Week 3. Mahomes has returned to weekly QB1 status, although the team could look to continue its dominance on the ground against a week opponent.