49ers ruled out Kyle Juszczyk (knee) in Week 4 against the Broncos.

04 October 2026

Juszczyk suffered what looked to be a serious knee injury in the fourth quarter and didn’t return to the game after being helped off the field. He would constitute an outsized loss for Kyle Shanahan’s offense, particularly his run game designs. A long-term absence for the trusted Shanny fullback could be something of a blow for Christian McCaffrey’s weekly prospects.