NFL Network’s Ian Rapoport said Deebo Samuel (hamstring) will have an MRI on Monday.

12 October 2026

The MRI will help determine the severity of Samuel’s injury, but the 30-year-old receiver is likely looking at a multi-week absence after he was quickly ruled out of Sunday’s game. Samuel has caught 16 passes for 206 yards and three touchdowns this season for the Niners while adding another 78 yards on nine carries. He seems unlikely to play in Week 6 against the Commanders, which means we could see an increased role for either Jacob Cowing or Brandin Cooks, who scored in Week 5’s win over the Seahawks.