Matthew Stafford completed 40-of-54 passes for 383 yards and three touchdowns in the Rams’ 37-34, Week 5 loss to the Bills.

13 October 2026

It was the third consecutive game in which Stafford attempted 51 passes or more in what has become the most voluminous passing offense in the league. The two powerhouses felt each other out throughout the first half as only 20 combined points per scored before the break. Things would get aggressive for the final 30 minutes as seven combined touchdowns were scored on nine second half possessions, four of which were accounted for by the Rams. Stafford directed a whopping 24 targets toward alpha wide receiver Puka Nacua, who set a career high with 17 receptions in a short-area role. The reigning MVP returned an instant classic performance against the 2024 MVP, ultimately coming up short in overtime following a blocked field goal attempt from Harrison Mevis. The Rams fall to 2-3 ahead of a home matchup against the more forgiving Cardinals in Week 6. Stafford is once again a fantasy QB1 in that matchup.