Chargers coach Jim Harbaugh said Derwin James (hamstring) is a candidate for injured reserve after suffering a setback.

28 October 2026

Brutal. This team cannot catch a break. Losing James makes the center of their defense fairly vulnerable. The Chargers’ stalwart safety plays a do-it-all role. If James lands on injured reserve this week, he will be eligible to return for the Chargers’ Week 12 game against the Patriots.