Isiah Pacheco (shoulder) has been ruled out for Week 14 against the Bills.

08 December 2023

The Chiefs will be without one of their biggest playmakers in one of their biggest matchups of the season, as Pacheco has already been ruled out for Week 14’s contest against the Bills. Pacheco has handled 58 percent of the Chiefs’ backfield rush attempts this season, with Clyde Edwards-Helaire coming in second with 14 percent of the team’s carries. With Pacheco out, we’d expected Edwards-Helaire, a former first-round pick, to handle the majority of early-down rushes while Jerick McKinnon serves as the third-down/pass-catching back. McKinnon posted a career-high 56 receptions for 512 yards last season and was one of Patrick Mahomes’ favorite targets down the stretch. He could have some high-end RB3 upside in PPR leagues in a game that should feature plenty of scoring.