Joe Mixon (ankle) will not play in Week 5 against the Bills.

04 October 2024

Mixon returned to practice for a limited session last Friday before being listed as questionable. He did not suit up on Sunday but the return gave fantasy managers hope that he would be ready for Week 5. That was far from the case as Mixon didn’t practice it all this week and was ruled out entirely on the final injury report. His status for Week 6 is up in the air as well. Dameon Pierce is questionable this week, making Dameon Pierce a risky fantasy bet versus the Bills.